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Frequently Asked Questions about Spironolactone
Spironolactone is a "Potassium Sparing Diuretic" that has been used for decades to treat high blood pressure and fluid retention. 2. How does it help patients with hair loss? There is much scientific data showing the beneficial effect of Spironolactone on hair loss. Spironolactone has been noted to have anti-androgen activity. Androgenetic alopecia (male and female patterned baldness) is heavily influenced by androgens (most specifically- DHT). Spironolactone binds to the receptor sites on the hair follicles which blocks DHT from having its miniaturizing affect on the hair follicle. 3. What are the side effects of Spironolactone? The side effects are minimal now that Spironolactone has been made into a topical solution, instead of a pill. Rarely, a patient will develop a rash from the Spironolactone solution and, therefore, will need to stop this solution. Another downside is the products "malodorous scent". This odor is increased if Spironolactone is combined in the same container with other chemicals (i.e.- Minoxidil, retinoic acid). 4. How and when do I use Spironolactone solution? 1 cc of the solution should be applied to the balding scalp twice a day. It should be applied and allowed to dry (few minutes) before placing on the minoxidil solution.
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